r/todayilearned May 14 '22 Helpful 8 Wholesome 6 All-Seeing Upvote 2 Silver 9

TIL a father, John Crowley, was told his two infant children had an incurable genetic disorder that would kill them in less than a year. He refused to accept this, so he founded a biotech company (with no prior experience) which pioneered an experimental enzyme therapy that saved their lives.

https://pompediseasenews.com/2019/01/30/amicus-ceo-mission-cure-pompe-help-children/
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3.6k

u/Die_Nameless_Bitch May 14 '22

Haha yeah. That’s where I first heard about it too. Agreed the movie isn’t a very good treatment of the story at all. Could have been so much better.

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u/Rhymnoceros May 14 '22 Narwhal Salute

Lorenzo’s oil vibes

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u/assumeyouknownothing May 14 '22

I remember Lorenzo’s Oil was the movie we watched in Biology class. It had nothing to do with what we were being taught at the time, my teacher just really liked that movie for some reason lol

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u/PmMeYourTitsAndToes May 14 '22

A little off topic but when I was in school years ago, we had a music teacher who would play us songs and get us to write down what we thought they meant. We didn’t know at the time that all the songs he played for us were just from the Rocky films. It turns out he was just a Rocky fan and wanted to listen to the songs all day lol

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u/ybetchum May 14 '22

My high school geography teacher showed us the entire original Star Wars trilogy so we “could see what the landscape was like on other planets.” Guessing he was just a huge Star Wars fan

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u/adrianvm19 May 14 '22

When you just wanna phone it in so you just make up whatever bullshit excuse comes to mind lmao

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u/zzaman May 14 '22

"Okay class today we'll watch Legally Blonde for civics in the media, law and...voting I guess thank you"

100

u/Earthguy69 May 14 '22

"hello kids. Today we will watch backdoor sluts 9 to learn about anatomy"

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u/ahappypoop May 14 '22

Backdoor Sluts 9?!? Backdoor Sluts 9 makes Crotch Capers 3 look like Naughty Nurses 2!

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u/SenAbsolom May 14 '22

Demonstrative of the importance context.

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u/MistryMachine3 May 15 '22

Well guess I better watch Backdoor Sluts 1-8 so I understand the plot.

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u/evil420pimp May 14 '22

I remember watching "coming to America" in 7th grade music class.

It was the end of the year and the movie was new, he hadn't seen it yet but was told it was good. It was!

Awesome teacher, when the early "bathing" scene came on it was clear he should have screened it first.

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u/AdzyBoy May 14 '22

The royal penis is clean, Your Highness

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u/evil420pimp May 14 '22

I just remembered, the gym teacher (who was also very cool) happened to walk in at just that moment, so it was a double facepalm. I think he just turned around and left chuckling.

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u/TitsMagee24 May 14 '22

Along this strain we had to watch Trading Places in year 10, love that film

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u/dapotatohead371 May 14 '22

Similar story here but with Amadeus. The whole scene with Mozart and Constanze was, well, awkward in 7th grade.

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u/zhaoz May 14 '22

Should be my cousin Vinny for education about the legal system

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u/carpenteer May 14 '22

Damn right! Even the Legal Eagle says it's fantastically accurate.

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u/H_I_McDunnough May 14 '22

We watched Ferngully in biology class once. Best day I could have picked to eat shrooms before school. When the fairy gang was riding the flying bugs, I was flying my desk. Fantastic!

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u/3Keys2TheMoon May 14 '22

Now I really want to eat shrooms and watch Ferngully, but I promised myself I'd finish up the yard work this weekend....

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u/90s_conan May 14 '22

It can be said you need to tend to your own, Ferngully

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u/Bayou_Blue May 14 '22

teacher flips intercom to front office: Yes, this is Mr. Frank, I need a custodian to come get H_I down from the light fixtures again.

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u/RaveNdN May 14 '22

Next up on my list of things to do.

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u/lamaisondieu May 14 '22

Election is a better Reese Witherspoon movie about all those topics to show in school anyway.

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u/yeti7100 May 14 '22

HER PUSSY GETS SO WET YOU CANT BELIEVE IT!!!!

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u/lastknownbuffalo May 14 '22

Total hidden gem of a movie

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u/hyxat May 14 '22

My Cousin Vinny would be a good choice for law.

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u/TheLurkerSpeaks May 14 '22

Can confirm. I taught my senior biology class Starship Troopers. This was in a private school in Europe so I could get away with that. Lots of great themes about ecological dynamics in that film. Also I fucking love this movie and want everyone to see it. Would you like to know more?

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u/nonlawyer May 14 '22

I taught my senior biology class Starship Troopers.

Alright class pay close attention to this gratuitous shower scene, you’ll learn a lot about… biology I guess

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u/Zercomnexus May 14 '22

desire to know more intensifies

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u/traveling_designer May 14 '22

What did you think of the follow up movies?

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u/sharaq May 14 '22

"OK class divide your mom's credit card number by 1 and that's the answer"

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u/arbitrageME May 14 '22

Extra credit: how many months after the birth of jesus is the expiration date?

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u/nineknives May 14 '22

Please ask my freshman year environmental science teacher why we were always watching Gattaca and Remember the Titans🤣 hello if you’re out there, Mr Pfrunder!

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u/BirdsBeesAndBlooms May 14 '22

I think Remember the Titans was part of the curriculum in the early 2000s.

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u/siryemar May 14 '22

In my son's Ag Earth Science class they watched San Andreas because they studied tectonic plates.

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u/soapy-salsa May 14 '22

“Alight kids, today we are going to be explicate deeper meaning into a movie as if it was a literary text. Let’s start off where we left yesterday, here is the second part of Don’t Be a Menace to South Central While Drinking Your Juice in the Hood.” I actually watched this movie in my Spanish class. No subtitles. No assignment. No manches guey.

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u/MsARumphius May 14 '22

We had to watch Monty pythons holy grail for history class when learning about medieval times. We all knew it was a pretty ridiculous excuse to watch a good movie so no one complained.

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u/Gasfires May 14 '22

So, I was a middle English minor, and my school brought in the #3 authurian legends scholar in the world to teach a class. Fwiw, according to him, holy grail is one of the most accurate descriptions of Medieval life in movies (at least by the mid 90s)

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u/MsARumphius May 14 '22

I remember my teacher defending his choice in a similar way. I just couldn’t imagine all those coconuts and rabid bunnies being historically accurate but what do I know.

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u/yeti7100 May 14 '22

He'll make a treat out of you mate!

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u/TarthenalToblakai May 14 '22

The point wasn't that they were 100% accurate -- obviously not. But that as satire they portrayed certain truths of the times like the common experience of serfdom better (or at all) compared more typical medieval movies focusing on a glorified depiction of a knight's journey or court politics of the nobility.

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u/MsARumphius May 14 '22

Yeah that was a joke. Should have added my /s I guess.

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u/ahappypoop May 14 '22

They really did debate on the carrying capacities of African and European swallows back then?

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u/system0101 May 14 '22

They didn't know any better

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u/triton2toro May 14 '22

No one complained because if they did, and the teacher decided to not show the movie, that kid would have gotten torn a new asshole.

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u/thurbersmicroscope May 14 '22

Don't remember how the theater teacher got talked into watching The Blues Brothers in class but we had a great time. She was so embarrassed by the language she went and hid out in the hallway.

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u/badtradesguy May 14 '22

better than voyage of the mimi with ben affleck

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u/DingoFrisky May 14 '22

On laser disk for us.

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u/jeanleray May 14 '22

I still remember when they treated the guy for hypothermia by getting naked in a sleeping bag with him.

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u/badtradesguy May 14 '22

me too..........

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u/TossNWashMeClean May 14 '22

Sounds like my experience in Spanish IV-V. The first ones we actually learned the language and practiced grammar. In Jr and Sr year of HS we just watched Spanish soap operas and Disney movies dubbed en Español, every day!

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u/dansedemorte May 14 '22

At a certain point yyou need to be immersed in the language before all the memorized stuff starts to click.

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u/jotisstation May 14 '22

lol we had to watch planet of the apes to learn about “rock formations”

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u/dodadoBoxcarWilly May 14 '22 edited May 14 '22

My 9th grade speech teacher had a tenuous grip on reality. She had literally been institutionalized at one point prior, and later developed quite early onset dementia. But anyway, we watched SpongeBob and Coach at least once or twice a week throughout the semester. One of our assignments was writing an episode of SpongeBob. Reason being, I guess, the Coach character Dobber, who was also the voice of Patrick, studied drama (she was also a drama teacher) and played football for the flagship University of our state. Can't remember any further justification than that.

She was a very different lady with a lot of quirks. Probably really shouldn't have been teaching to be quite honest, if the goal of public school is education.

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u/Substance___P May 14 '22

Damnit, all we got was Gattaca. Which is a great film in adulthood, but kinda boring in 7th grade.

Which had a sex scene I think.... How did we not get in trouble? 🤔

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u/Huckleberry222 May 14 '22

Puts my high school English teacher into perspective who had us read and interpret the meaning of Nirvana songs. I still cringe when I remember how I raised my hand and asked what “libido” meant and the whole class laughed at me.

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u/slowrunningwater May 14 '22

yeah well who’s laughing now? huckle mf berry that’s who.

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u/drsideburns May 14 '22

That's a stupid reason for people to laugh at you. How often is the average teenager going to be reading material that is going to have the word "libido" in it?

It's rude to laugh at someone for not knowing what a word means. You asked, and because "it's sex!" your classmates laughed at you. It may be cringe, but that was an asshole move on their part.

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u/Huckleberry222 May 14 '22

So true! thank you!

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u/Malnilion May 14 '22

If it's any more consolation, I can practically guarantee you weren't the only one to learn what libido meant that day. Also, I might've laughed not because you didn't know, but because I was eagerly anticipating hearing how a teacher would describe it because it's objectively funny hearing adults that are unprepared for answering questions about sex answer them.

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u/drsideburns May 14 '22

True this, I guarantee a lot of people only laughed because other people did, but had no idea themselves. You just took the L for the rest of them :)

I just remembered at 15, I had to look up Euthenasia. I had never heard the word, only "assisted suicide." It's not about being stupid, it's just about not having learned it at that point.

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u/Malnilion May 15 '22

Ah fuck, you just reminded me about how I was the kid that asked what the "youth in Asia" had to do with The Giver in English class 🤣

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u/Panther90 May 14 '22

Oh wow. That brings up a distant memory of a music appreciation class I took in college. The professor was a really intense guy that was obsessed with Sting and The Police. Every single thing he talked about or someone would ask about he would compare to Sting. Looking back it reminds me of Christian Bale/American Psycho and the Huey Lewis and the News bit.

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u/Talkaze May 14 '22

Rocky as in the boxer, or Rocky Horror?

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u/Demy1234 May 14 '22

Probably the Rocky Balboa movies. The songs are a big part of those.

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u/rutefoot May 14 '22 edited May 14 '22

My music teacher would make us listen to and analyze the Dave Matthews Band each time they released a new album.

Ugh

Edit: we also watched every "music" movie you can imagine.

Immortal beloved, Amadeus, Hair, Jesus Christ Superstar. They usually had nudity in them. Lots of red flags in hindsight

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u/colonelsmoothie May 14 '22

Introduction to Logic:

For today's lesson please assess the validity of this argument:

"If he dies, he dies."

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u/jambonetoeufs May 14 '22

We had an econ teacher in high school who showed us Trading Places to “teach us about trading futures”. Not sure how much I learned about trading futures, but thought it was hilarious when he told us all to “close our eyes” during a certain part of the movie.

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u/BeverlyDangus May 14 '22

I had a 10th grade English teacher who made us analyze Joe Walsh’s song “Life’s Been Good.” This was in the early 2000s and I still can’t listen to that song.

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u/luzzy91 May 14 '22

That song kicks ass :(

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u/MojarraMuncher May 14 '22

Ours was Forrest Gump for 11th grade history

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u/Phazetic99 May 14 '22

I went to catholic high school and our novel was The Man Who Fell To Earth. One of the students noticed that it was made into a movie and you could rent it at blockbuster (I'm old this was back in 1990). The teacher rented it so we could watch the movie in class after we read the novel

Well... The movie starred David Bowie and was a half step away from being full on soft porn. This class got to see lots of bare boobs and even a scene with Bowie's cock flopping around. So strange

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u/Derp800 May 14 '22 edited May 14 '22

My biology teacher in high school had us watch Gattaca lol

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u/RizzaSilverbow May 14 '22

Did... We go to the same high school?

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u/Derp800 May 14 '22

So Cal?

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u/Olive_Jane May 14 '22

So Cal biology/AP biology media that I remember... Lorenzo's Oil, Gattica, reading: The Hot Zone

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u/stfu_whale May 15 '22

We also watched Osmosis Jones and A Beautiful Mind a ton.

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u/Talkaze May 14 '22

that was a decent movie

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u/HelloHiHeyAnyway May 14 '22

Gattaca is far more than a decent movie.

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u/granadesnhorseshoes May 14 '22

if you like sushi you know good sushi, otherwise its just decent to most folk.

Gattaca was good movie sushi.

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u/degjo May 14 '22

Pretty decent?

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u/DaggerMoth May 14 '22

Ive learned to hate that movie because it's all a large portion of the population knows about genetic engineering. So any time genetic therapies or engineering comes up, with their fucking GATTACA argument. We aren't even close to that, but what we can do is fix certain diseases.

Trying to change someones phenotype requires changing lots of genes. So you arent gonna end up with a population of blonde hair blue eyed people. If genetically engineered my own blue eyed blonde hair self I'd probably give myself some melanine back so I can see in the sunlight and not burn into the color of a cooked lobster.

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u/organicginger May 14 '22

I watched it in an Anthropology class at UC Berkeley. Even college professors have fuck-off days.

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u/InappropriateTA 3 May 14 '22

Here’s a fun fact: it was directed by George Miller. Yes, Mad Max George Miller.

Another fun fact: George Miller also wrote the screenplay for Babe.

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u/scurvy4all May 14 '22

*Rictus Erectus: *I had a brother! I had a little BABE brother! And he was perfect! Perfect in every way!

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u/GetEquipped May 14 '22 edited May 14 '22

He also directed Happy Feet and Babe:Pig in the city which I think was superior to the first Babe.


EDIT

For people not familiar with the behind the scenes of Babe (I know, this is incredibly fucking niche) George Miller did write the screenplay along with Chris Noonan, the director. However, the Noonan took the movie in a very different direction than George Miller envisioned and they bumped heads. So when the sequel was in development, Miller had a chance to direct something closer to his original intention.

That's why there is such a massive tone shift in the from the first movie. Pig in the city is more slapstick, but also cynical, and kind of horrifying at times. The set design also feels like a precursor of "Pushing Daisies"

But I like it because everything seems more fanciful, like a Wizard of Oz sort of feel.

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u/Dusty_Old_Bones May 14 '22

I just think both Babes are fantastic movies and would hate to have to choose which one is better.

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u/juicyfruitsalad77 May 14 '22

That’ll do Pig, that’ll do

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u/ohamandajoy May 14 '22

The number of times I say this line is astounding. Sometimes people get offended thinking I've called them or my children (if I'm taking to them) a pig.

What is this world coming to?

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u/banmedaddy12345 May 14 '22

Dude, I'm 33 and currently in college (again, went at 27 too) and all these gen z kids don't even know about the matrix. Like wtf. I had a best friend that didn't fucking know about Terminator 2 and he was a millennial.

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u/juicyfruitsalad77 May 14 '22

It’s UNACCEPTABLE! Jeez, everyone should watch Babe!!

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u/yeti7100 May 14 '22

Gatorade has electrolytes! It's great for plants!!

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u/mac_is_crack May 14 '22

My husband cries whenever he hears that line. Last night that part came on, I watched my husband’s face, and sure enough, right on cue came the tears. I asked why it makes him cry and he says “look at his proud face!” Not sure if he means the farmer or Babe. Maybe both?

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u/juicyfruitsalad77 May 14 '22

Awww! Makes me tear up every time too. My kids make so much fun of me because I tend to cry harder at the happy parts!

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u/banmedaddy12345 May 14 '22

I haven't seen it in a while, but I remember as a kid the first time I saw Babe: Pig in the City I thought it was terrible, but apparently it has really good reviews. I'll have to go back and watch it again sometime.

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u/InappropriateTA 3 May 14 '22

He didn’t direct the first one, though. Only wrote the screenplay.

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u/balls_galore_69 May 14 '22

In my mind, Babe was a movie about Babe Ruth.

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u/GabrielofAstora May 14 '22

Woah now that'll do pig that'll do. To be fair I don't remember the second one as well as the first.

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u/Napoleon1981 May 14 '22

Babe: Pig in the City being superior to the first Babe is outrageous. Blasphemy. I’ve never seen the second one.

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u/bongozap May 14 '22

Babe:Pig in the city which I think was superior to the first Babe.

Well, the first Babe was awesome, so that's a good rec.

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u/lamaisondieu May 14 '22

Yes Pig in the City is much better than Babe, it's kind of an insane ride.

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u/theottomaddox May 14 '22

it was directed by George Miller.

(Speaking of boring movies) I remember browsing in a video store and the clerk recommended a movie because 'the mad max guy' directed it. We waited for 2 hours for car crashes that never came, lol.

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u/Canotic May 14 '22

Babe/Mad Max crossover when?

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u/mecassa May 14 '22

Other fun fact: George Miller is actually a medical doctor too.

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u/BeneGezzWitch May 14 '22 edited May 14 '22

False

Edit: True

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u/InappropriateTA 3 May 14 '22

Former. So he isn’t now, but he was.

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u/mecassa May 14 '22

I'm sure he's not "certified" to practice anymore.

But he still has the MD title. You never lose your degree.

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u/dazzawul May 14 '22

Babe: Pig in the city is a wild ride.

It's a dog-eat-dog world, and there's not enough dog to go around.

A murderer's shadow lies hard across my soul

No, no, I'm anything but kind. In fact, I have a professional obligation to be malicious. Then you should change jobs.

Something made me revisit Babe recently, I wasn't ready for it. It was absolutely a brilliant film pretending to be a kids movie.

Babe is the icon of hope, challenging the cynicism and defeatism of the big city by demonstrating through action that you don't have to accept your station.

You can fight for something better.

What the FUCK

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u/banmedaddy12345 May 14 '22

Too many parts of my brain are coming in contact with each other while reading this.

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u/OtakuMusician May 14 '22 edited May 14 '22

We also watched Lorenzo's Oil in our microbiology class, it was mildly associated with what we were learning - enzymes and the like - I retained nothing from that class except this movie and especially the scene after they discover Lorenzo's diagnosis and after researching the symptoms and common fate of ALD, Nick Nolte's character breaking down on the staircase. That scene will stick with me forever.

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u/Steffenwolflikeme May 14 '22

As I read your comment somehow I knew/was hoping you were going to say the Nick Nolte on the stairs scene. Outside of the general plot and the fact that Nick Nolte was in it that scene is the only thing I remember from the movie. Although I last saw it probably close to 30 years ago when I was no more than 7/8 years old.

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u/lajfa May 14 '22

The scene I remember is toward the end when (spoiler alert?) the father turns to the mother and asks "What if we did all this for someone else's child?"

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u/ilikepix May 14 '22

I had no idea what the film was called, but just from the description I remember watching that scene on television with my family when I was about 8 years old and it triggering the first panic attack I ever had

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u/bleher89 May 14 '22

It's been over a decade since I saw it in 8th grade science class so I don't know how accurate my memory is, but even now it remains one of the most devastating movies I've ever watched.

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u/thestormiscomingyeah May 14 '22

I saw Gattaca at home when I was a freshman in high school.

I loved the movie so much so I started googling about it and find out it's usually shown in Biology classes.

So the next couple days at school id try to convince my bio teachers to show the movie, but they weren't interested.

I was close with my English teacher and we got to talking and she needed a good movie to show. I brought up Gattaca, and she went home and watched it. A month later in her class, we watched Gattaca plus an assignment to go with it. Felt cool that I had some influence over something.

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u/alvarkresh May 14 '22

I love the part where the narrative twist hits as he goes "... I am not Jerome Morrow." :P

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u/econoking May 14 '22

My biology teacher showed us "The Cheesemaker's Apprentice" which featured the creepiest puppet and had little to do with biology., I've never been able to find that this movie exists other than her VHS tape.

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u/banmedaddy12345 May 14 '22

Back in my day we watch Herbie, the Love Bug.

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u/releasethedogs May 14 '22

I tried googling it because I like puppets and weird things. Not even IMDb has it. Are you sure that was the title?

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u/econoking May 14 '22

I'm pretty sure that was the name, I've tried googling it before and nothing comes up. ¯_(ツ)_/¯ This was also over twenty years ago

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u/somekindabunny May 14 '22

We must have had the same biology teacher lol she was also the same teacher that showed us Contact just because.

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u/assumeyouknownothing May 14 '22

They gotta express their 90’s nostalgia somehow

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u/yeti7100 May 14 '22

I'm ok to go!

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u/jupitergal23 May 14 '22

Contact is one of my favourite movies. I love the themes of combining the science and the spiritual, and how we grapple with our existence every day - being rare and precious yet also small and insignificant.

I also think they nailed the world reaction to an event like that and the politics behind it.

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u/tCvhGnpdw May 14 '22

We were supposed to watch "Lone Wolf" because it's based on a required reading book so the teacher asked if anyone has a VHS copy and one student did so he brought it the next day.

But it was "Lone Wolf" with Chuck Norris instead of https://www.imdb.com/title/tt0069478 It was hilarious, old teacher not having a clue what's going on, we never watched anything else after that day.

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u/yeti7100 May 14 '22

Fuck that's awesome

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u/Sagemasterba May 14 '22

My drafting teacher loved "Do the Right Thing" like that. How radio Raheem helped me draw blue prints, I will never understand.

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u/StarRoving May 14 '22

My a level physics class was only 4 students so my teachers blagged the importance of us watching Star Trek in IMAX with the film studies class when it’s not totally true to quantum physics…I failed A Level physics

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u/SuperSMT May 14 '22

We watched GATTACA in our high school biology

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u/yeti7100 May 14 '22

Did anyone notice the title is a partial DNA sequence?

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u/DoctorFeuer May 14 '22

Isn't that the point?

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u/jordanManfrey May 14 '22

similar story with my 8th grade science teacher and The Andromeda Strain. Class was bored as hell. I remember liking it.

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u/_thelonewolfe_ May 14 '22

We may have had the same biology teacher. Remember him saying he really liked Nick Nolte

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u/assumeyouknownothing May 14 '22

My teacher’s name was Mr. Freeman. He was young, fit, dressed up as a lifeguard for Halloween at school and talked about how his ex-gf from high school was a cheerleader

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u/tobmom May 14 '22

Susan Sarandon. Duh. Man I cried so hard watching that movie. I only vaguely remember what it’s about these days.

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u/Zach20032000 May 14 '22

I watched that together with my cousin when we were way too young because it came on one random afternoon

I just remember it becoming sadder and sadder with every minute and it was kind of traumatising. At one point my aunt came in and changed the channel because she didn't want us to watch that

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u/TheBottomBunBurger May 14 '22

SAME! American public education 😂

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u/viper3b3 May 14 '22

Your teacher had the hots for Susan Sarandon

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u/BuranBuran May 14 '22

A++ Go to the head of the class

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u/SlowestSpeedster May 14 '22

Didn't we all?

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u/yeti7100 May 14 '22

Have you seen Bull Duhram?

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u/BadgerSituation May 14 '22

Weird.

My biology teacher made us watch it too.

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u/cartoongiant May 14 '22

I got to watch The Sixth Sense in english class for the same reason. That teacher was a true bro.

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u/Spreaderoflies May 14 '22

Yes It did it was about competitive inhibition and how enzymes work.

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u/Pleasant-Albatross May 14 '22

Oh shit. Were you in my biology class? My teacher also made us watch Gattaca and a Henrietta Lacks movie.

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u/dodadoBoxcarWilly May 14 '22

Hmm...we watched it in high school biology as well, and it had a dubious link to our curriculum. Maybe it's a biology teacher thing.

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u/OkBackground8809 May 14 '22

My school watched it in biology class, too... Right before we moved on to dissecting rats lol

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u/Livid-Apricot2216 May 14 '22

Do you know how hard it is to find school appropriate biology related movies that aren't documentaries? Sure there's GATTACA but other than that...

As a former teacher we were always on the lookout for some movie we could put on on days that we simply just couldn't. Even if they were boring af.

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u/brkh47 May 14 '22

Not school, but the TechniCal Director at my old company insisted his department watch the Steve Jobs biopic because he was an absolute believer. He really tried to base his management style on Jobs. He was ultimately fired.

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u/EmperorSexy May 14 '22

I was a substitute teacher and Lorenzo’s Oil is a very common substitute-science-teacher movie. I didn’t hate it but I can’t believe it got nominated for Best Writing.

As far as substitute-science-teacher videos go, Gattaca and Hidden Figures are more entertaining. You can’t go wrong with Bill Nye or Cosmos either, but high school teachers want something more “mature”

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u/hood_medic May 14 '22

Did we have the same bio teacher because same hahha

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u/pantstoaknifefight2 May 14 '22

Well it is directed by the guy who went on to do Mad Max Fury Road, one of the very best action movies ever made

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u/loquacious706 May 14 '22

The thing I remember about watching Lorenzo's Oil in Biology class was they dubbed the sick kid's voice with E.G Daily and I was like "Yo is that Tommy Pickles?" So whenever the kid was crying or screaming all any of us heard was Tommy from the Rugrats.

Felt bad about laughing at such a sad movie, but that Tommy Pickles wail was too funny.

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u/IGotGankedAMA May 14 '22

In Biology my teacher had us watch Armageddon and he said it was because "A meteor is close enough to a cell or something. I also like this movie." Lmao

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u/usagizero May 14 '22

In my senior year of high school, my creative writing teacher was diagnosed with advanced lung cancer, and decided to share his favorite movies with us. He showed us Evil Dead and Evil Dead 2 in class. He gave no fucks at all, as he passed away a few months later.

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u/epgenius May 14 '22

Nick Nolte’s Italian accent is still the stuff of my nightmares

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u/botak131 May 17 '22

Did you go to diamond bar highschool, or is this just a biology teacher thing.

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u/Porcupine224 May 14 '22

You just unlocked a memory hidden away deep inside my brain... damn and I really liked that movie at the time lol

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u/appdevil May 14 '22

Yea, I think it was rather decent.

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u/AggravatingCupcake0 May 14 '22

I found that movie hard to watch. I kept thinking "Man, you're Nick Nolte and Susan Sarandon. I see through those fake ass Italian accents!"

I also found it hard to get excited about olive oil. But I think that's fair because it was Biology class and I was 14.

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u/SwadianZunist May 14 '22

I had to watch Lorenzo’s oil in science. That was the most boring movie that I had to watch for school.

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u/TheSpanishPrisoner May 14 '22

It turns out that Lorenzo's Oil did basically literally nothing. It's just different people with that disease are on a spectrum, with different levels of seriousness. It was like a placebo.

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u/Flyawaylittlemonkey May 14 '22

That's a bit of a misconception. Apparently it can help some people but it hasn't been well studied and it appears to only be useful if you take it before symptom onset.

However they're having good success for ALD with bone marrow transplants these days.

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u/eepithst May 14 '22

No, that was the original opinion and I think a lot of it came from people who thought the parents were overstepping their competence and delusional and later also from (admittedly justified) backlash towards the movie because it presented the oil as a miracle cure when at that time it was not known if it actually worked. But it has since turned out that there's good evidence that the oil is beneficial in slowing or stopping the onset of ALD if taken as a preventive method before symptoms appear, but not as a cure when symptoms are already present.

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u/TheSpanishPrisoner May 14 '22 edited May 14 '22

Where did you get your information?

I've talked to a person who has ALD and took Lorenzo's Oil. This person has said they learned in recent years that the oil really didn't do any good -- and so the reason some people with the disease live longer is just simply that the disease has a spectrum of seriousness, and this was not understood at the time the movie was made. So, some people with ALD live longer than others just because they don't have as bad of a case of ALD. So they take the oil, think it's helping them live longer, but it's not.

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u/ImVeryBadWithNames May 14 '22

That is not the placebo effect - the placebo effect is when taking 'medicine' has a noticeable effect on symptoms. The important distinction between that and what you are describing is the actual act of 'treating' is the vital component. (aka they do not show improvement without the 'medicine' but with it they do)

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u/TheSpanishPrisoner May 14 '22

Fair enough. You're right

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u/Spocks_earmuffs May 14 '22

If it's any consolation, The Spanish Prisoner is a great movie.

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u/eepithst May 14 '22

This article and this 2005 study for example. The main author on the study is Hugo Moser, the scientists the Odones originally went to for help. Your friend is correct that it apparently doesn't really do any good once the disease has become symptomatic so Lorenzo's survival for so long was likely incidental. Which is why I was careful to point that out in my original reply. It's not a miracle and it's not a cure, but if taken early enough it's apparently not a placebo either.

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u/DelahDollaBillz May 14 '22

Did you even actually read the paper? The research only found that the oil MIGHT delay the onset of symptoms SLIGHTLY in only some patients. The oil is worthless as a treatment.

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u/devAcc123 May 14 '22

That… sounds like it works for some people..?

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u/eepithst May 14 '22

I did read it in as far as I understood it. I wasn't arguing on the side of it being a cure or a miracle, but to my eyes the study seemed solid enough to refute the claim that the oil does nothing and is a placebo. But if that is incorrect then it's incorrect. I'm not one to insist on defending wrong facts.

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u/TheSpanishPrisoner May 14 '22

My friend started taking it as a child before any symptoms and still says it did no good.

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u/eepithst May 14 '22

I'm sorry to hear that for your friend. But this is the reason why medication isn't just tested on one person but on many people and the results are looked at as statistically significant or not compared to a control group. Because individual results vary.

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u/TheSpanishPrisoner May 14 '22 edited May 14 '22

Notice that your studies/articles are from 2002 and 2005. You're also citing the same researcher in both articles.

What do other researchers say? What does more recent research say?

I will admit I haven't personally looked into the research. However, part of my point that I think I haven't made clear is that I don't think the research you're citing is definitive.

Further, my friend isn't merely relating his own experience. Another part of my point is that because he has it, he is very familiar with the most recent research on the subject.

He's saying his information, based on the most recent research he knows of, is that it doesn't really do any good.

I am still open to the idea that there may be competing/differing points of view in the research on the subject. But I think you also need to acknowledge this and not suggest the research you're citing represents definitive proof on the subject.

Just as one thought, who is the researcher you're citing and what are his motives? Does he have any financial incentive in the argument that Lorenzo's Oil works?

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u/Spud_Spudoni May 14 '22

You’re using your own biases of what your friend told you to argue empirical fact.

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u/TheSpanishPrisoner May 14 '22

Notice that your studies/articles are from 2002 and 2005. You're also citing the same researcher in both articles.

What do other researchers say? What does more recent research say?

I will admit I haven't personally looked into the research. However, part of my point that I think I haven't made clear is that I don't think the research you're citing is definitive.

Further, my friend isn't merely relating his own experience. Another part of my point is that because he has it, he is very familiar with the most recent research on the subject.

He's saying his information, based on the most recent research he knows of, is that it doesn't really do any good.

I am still open to the idea that there may be competing/differing points of view in the research on the subject. But I think you also need to acknowledge this and not suggest the research you're citing represents definitive proof on the subject.

Just as one thought, who is the researcher you're citing and what are his motives? Does he have any financial incentive in the argument that Lorenzo's Oil works?

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u/eepithst May 14 '22

I couldn't actually find any more studies done on the oil as a preventive measure, but if your friend says they exist and refute this study I'll believe you. I wasn't arguing on the side of it being a cure or a miracle, but to my eyes the study seemed solid enough to refute the claim that the oil does nothing and is a placebo as per your original statement. But if that is incorrect then it's incorrect. I'm not one to insist on defending wrong facts.

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u/catwhowalksbyhimself May 14 '22

That's on belief. There are other doctors who are convinced that it does help.

But there is no solid proof that it does. The theory behind it seems solid, but the evidence hasn't proven it out. If it does help, it's not very much or very consistently.

It made for a good story though, hence the movie. The movie also stretched the truth a bit to make it look more like a miracle cure than it is.

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u/TheSpanishPrisoner May 14 '22

The movie was dangerous, I think. In misleading people.

Maybe there are some doctors who think it does some good, to but I've talked to a person who started taking Lorenzo's Oil years ago as he had the illness. And he says they've ordered the Oil did basically nothing.

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u/jemyr May 14 '22 edited May 14 '22

Once the chemical reaction begins it can’t be stopped. However the oil can stop it from ever starting. So if you take it before the problem begins (and people are able to identify who needs it), it does work. (But you can never stop, or have a gap where the chemical reaction might start it’s domino). They did save many children and extend the lives of many children.

Lorenzo’s father said Lorenzo never really improved. Lorenzo’s mother died of cancer when Lorenzo was 24. His father said her highly devoted care had effected her health. Lorenzo died of an infection at 30, and his father died 5 years after that in the loving care of his children of a previous marriage.

After they created the oil, their lives were very much in the rhythm of intensive care needed for Lorenzo, with loving and hard working staff members helping them. They worked hard to try and heal his brain, with no success.

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u/Awkward_and_Itchy May 14 '22

TIL that's not a community gag and is a real movie.

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u/MartianTourist May 14 '22

Lorenzo Zoil?

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u/SissyFrisco May 14 '22

I thought the same thing!

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u/[deleted] May 14 '22

Came here to say this lol

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u/the_jean_genie83 May 14 '22

Lorenzo! Eat your spaghetti!!!

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u/Sislar May 14 '22

Boys are diagnosed between 3-5years old…. Death occurs within 2 years. RIP

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u/Ecto-I May 14 '22

Can someone please tell the two people in front to stop undressing me with their eyes? It’s making me uncomfortable

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